Research Proposal. Crystal Parry Independent Research GT Title: Dementia Dilemma: The Effect of Anticholinergic Medications on the Aging Brain Introduction: The purpose of this research is compare four different acetylcholine supplements that have been shown to reduce or stop the effects of dementia in elderly adults caused by anticholinergic medications.5/5(1) Jun 15, · Research proposal for Alzheimer’s disease 1 RESEARCH PROPOSAL FOR ALZHEIMER’S DISEASE Student’s Name Professor’s Name College Course Date. Research Proposal For Alzheimer’s Disease 2 RESEARCH DESING IN HEALTH RESEARCH PROPOSAL FOR ALZHEIMER'S DISEASE Abstract Alzheimer Disease is considered as one of the world’s dangerous Research Methodology Research Question and Hypothesis o What is the correlation of environmental and lifestyle factors on the development of Alzheimers disease? o The exposure of aluminum (Al) in the environment accelerates the progression of Alzheimers disease (AD) because aluminum acts as a neurotoxin towards humans, cognitive decline is present in areas with metallic residue in waterways, 5/5(2)
Research Proposal | PDF | Dementia | Alzheimer's Disease
Crystal Parry Independent Research GT Title: Dementia Dilemma: The Effect of Anticholinergic Medications on the Aging Brain Introduction: The purpose of this research is compare four different acetylcholine supplements that have been shown to reduce or stop the effects of dementia in elderly adults caused by anticholinergic medications.
The best supplement appears to be phosphatidylserine in terms of restoring the cognitive abilities of dementia patients based on background research, alzehmers research proposal. Once this has been confirmed through data collection, it will be presented to caretakers of dementia patients. Background and Rationale: In todays society there has been a rise in dementia alzehmers research proposal elderly adults, especially in this country.
There also is not a definite cause of the start of dementia in the brain. As a result, there is constant research being done to find the cause of dementia. Various studies that claim to have found the cause of dementia arise everyday, so there is a vast amount of information on this subject. Many scientists have conducted such studies, and recently there has been research into the effects of anticholinergic medications of the cognitive abilities of elderly dementia alzehmers research proposal. Medical dictionaries define anticholinergics as a medication that blocks acetylcholine, a neurotransmitter that delivers signals to control bodily functions Cafasso, Researchers believe that by blocking neurotransmitters, anticholinergics are actually reducing its effects within the brain.
At the University of Indiana Medical School, dementia patients from the Alzheimers Disease Neuroimaging Initiative ADNI and the Indiana Memory and Aging Study IMAS.
Some of the participants took at least one medication with high anticholinergic effects, while others did not. Then, the two groups had their brain matter tested for cognition,glucose metabolism, and brain atrophy in order to determine the status of their Alzheimers. The subjects repeated this process after periods of 3, 6, and 12 months.
After conducting these tests, researchers came to the conclusion that the usage of anticholinergic drugs resulted in an increase in brain atrophy and cognitive decline, alzehmers research proposal, and that it should be encouraged to seek out different treatments Risacher, et al.
Another study conducted at the University of California came to the same conclusion Frontotemporal dementia, Consequently, acetylcholine supplements have been proposed as the solution to preventing or stopping the dementia that acetylcholine medications may cause. In a research report written by Dr. James Meschino, the clinical director at the RenaiSante Institute of Alzehmers research proposal Medicine, he describes four different supplements that are known to reproduce acetylcholine that is necessary for boosting cognitive abilities in those who have diseases related to dementia.
These include include CDP-choline, alzehmers research proposal, phosphatidylserine, Bacopa Monnieri, and Huperzine A. Meschino says that ingesting a [acetylcholine] supplement can help combat memory loss and other related problems Meschino, n. Dementia and other neurological diseases like Alzheimers are one of the leading causes of death today.
Since there is no cure for these diseases yet, any new research or information that can lead to one would be very beneficial to dementia patients and those who may develop the disease in the future.
If anticholinergic medications are in fact a cause of dementia, alzehmers research proposal. information will help them, their families, and physicians make informed decisions about what supplements they can take to reduce the potential of developing dementia while taking their over-the-counter medications.
Others who also know people dealing with dementia can share this information with them as well. Many people who have loved ones who have been living with dementia are eager to find ways to reduce or even stop its effects, and such information would be very helpful to them.
Research Methodology: Research Question: Which acetylcholine supplement will reproduce neurons in the brain to curb the development of dementia? Hypothesis: Phosphatidylserine will be the best acetylcholine supplement to reproduce neurons in the brain because of its use of fatty acids, which is necessary in reproducing the acetylcholine to recreate neurons. To support the research hypothesis, the ideal qualities of phosphatidylserine as an acetylcholine supplement and the use of studies done successfully with phosphatidylserine on improving the cognitive abilities of dementia patients will be discussed.
Research Design Model: Quantitative research methods will be applied in other to collect data, specifically evaluation. The independent variable is the use of the four acetylcholine supplements being evaluated; CDP-choline, phosphatidylserine, Bacopa Monnieri, and Huperzine A. The dependent variable will be the resulting cognitive behaviors of dementia patients after taking the supplements.
Choosing this model is ideal for this research topic since data will be necessary to understand which acetylcholine supplement made dementia patients perform better and compare them to one another.
Data Collection: Meta-analysis is the best way to collect data for this alzehmers research proposal, because it will be unlikely that access to subjects to collect data on would be available.
Therefore, looking at studies published in academic journals is a probable way to collect the data needed. Synthesizing the information found in these studies regarding alzehmers research proposal effectiveness of each supplement in restoring the cognitive abilities of patients Product Objectives: The information discovered through research will likely be a video that can be presented at a seminar.
Showcasing the research this way is a method in which information can be shared quickly and easily. Hopefully, it can be presented to directors of assisted livings or nursing homes, where dementia patients are being cared for. This target audience would need this information in order to select the best medications needed for their patients.
The presentation may last for 10 to 15 minutes, alzehmers research proposal, depending on what relevant information needs to be shared. Logistical Considerations: Print sources from medical periodic journals will be needed to complete this research project, and they may need to be paid for, if full access is not readily available only.
To share the final product with those who work in nursing homes or assisted livings, directors of such places of business should be contacted beforehand. Timeline In the third quarter, a timeline will be added that outlines the data collection, product development and audience.
References: Cafasso, Alzehmers research proposal. All about anticholinergics. Krucik Ed, alzehmers research proposal. Saykin, A. Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults [Abstract]. JAMA Neurology, 73 6. Anticholinergic medications: Frontotemporal dementia. In Frontotemporal dementia. Open navigation menu. Close suggestions Search Search. en Change Language close menu Language English selected español português Deutsch français Русский italiano român Bahasa Indonesia Learn more.
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Research Proposal. Crystal Parry Independent Research GT Title: Dementia Dilemma: The Effect of Anticholinergic Medications on the Aging Brain Introduction: The purpose of this research is compare four different acetylcholine supplements that have been shown to reduce or stop the effects of dementia in elderly adults caused by anticholinergic medications.5/5(1) Jul 07, · Alzheimer's Research Proposal 1. Slowing the Progression of Alzheimer’s Disease Using Gene Therapy José Enrique Ríos-Castillo RISE Program Prof. 2. Alzheimer’s Disease Alzheimer's disease is a progressive condition that destroys the connections between cells in 3. Jun 15, · Research proposal for Alzheimer’s disease 1 RESEARCH PROPOSAL FOR ALZHEIMER’S DISEASE Student’s Name Professor’s Name College Course Date. Research Proposal For Alzheimer’s Disease 2 RESEARCH DESING IN HEALTH RESEARCH PROPOSAL FOR ALZHEIMER'S DISEASE Abstract Alzheimer Disease is considered as one of the world’s dangerous
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